The biggest upset of the first round of the NCAA college basketball tournament has to be Ball State toppling Tennessee. In the women's tournament. The Lady Volunteers are the two-time defending champs and were 42-0 in the first two rounds of the tournament before being routed by the Cardinals, 71-55. While the Volunteers had lost 11 games this season, they were the fifth seed and strong favorites in the game; Ball State was the 12-seed. Upsets like this are few and far between in women's basketball. There tends to be a larger disparity of talent between the haves and the have-nots; and Tennessee has been in the "haves" department for many years.